The molecular mechanisms underlying synaptic plasticity ― the ability of neurons to change the strength of their connections ― can vary across different inhibitory neural circuits as much as they can vary across excitatory neural circuits, according to research presented this morning at the Society for Neuroscience meeting.

Lithium treatment reverses some of the behavioral and brain-cell abnormalities in mouse models of fragile X syndrome ― an inherited form of mental retardation that includes learning deficits, aggressiveness, and social withdrawal ― according to research presented today at the Society for Neuroscience meeting.

Targeting epigenetic mechanisms may offer potential new therapies for people with developmental disorders including autism, researchers said today at the Society for Neuroscience meeting.

Researchers at the Society for Neuroscience today described a new test for animal behavior that doesn’t interfere with normal mouse behavior, doesn’t require human interaction, and makes it simple to take long-term measurements: the ‘licking testʼ.

Mice missing a copy of GAP43, a gene involved in the development of axons ― the thin strands that conduct electrical signals between nerve cells ― show biological and behavioral parallels to autism, according to unpublished research presented in a poster session today at the Society for Neuroscience conference.

Treatment with the insulin-like growth factor (IGF) greatly improves the health of mouse models of Rett syndrome ― a regressive genetic disorder that causes mental retardation, seizures, and autistic features ― according to unpublished researched presented this morning at the Society for Neuroscience conference.

Schizophrenia may be a consequence of neuronal birth gone awry, according to unpublished research presented today at the Society for Neuroscience conference.

Research on mouse models published in the past year is paving the way to reversing the symptoms of some autism-related disorders, National Institute Health directors told a packed room of 80 reporters at the morning at the Society for Neuroscience conference.

A mouse model of neurofibromatosis ― a genetic neurodevelopmental disorder that leads to nerve tumors, memory problems and, often, autism ― exhibits deficits in social interaction and social learning, according to research presented in a poster session today at the Society for Neuroscience conference.

For decades, those who study brain cell activity have faced a fundamental trade off: either closely monitor the activity of a single cell or look at the circuit level to see how large groups of neurons communicate with each other.