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Spectrum: Autism Research News

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Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

July 2009

New autism gene points to cellular calcium imbalance

by  /  14 July 2009

A common variant of a gene called CACNA1G — which makes a channel that helps regulate calcium flow between cells — may increase the risk of developing autism, according to research published in Molecular Psychiatry.

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June 2009

Study links autism to stem cell development

by  /  23 June 2009

The molecular defects that cause some cases of autism may arise during the development of neuronal stem cells, according to a new theory bolstered by several independent animal and human studies.

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May 2009

Brain images uncover candidate genes for schizophrenia, autism

by  /  12 May 2009

Applying an emerging technique that combines genetic data and brain scans, researchers have identified two new genes involved in schizophrenia. The method, called ‘imaging genetics’, holds promise for linking genes to brain function in complex psychiatric disorders, including autism.

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Visual contrast drives face recognition, study finds

by  /  5 May 2009

The answer to a long-standing mystery in visual neuroscience may also help explain how people with autism perceive faces, according to a study published in March in the Proceedings of the National Academy of Sciences.

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April 2009

Amygdala in autistic brains may not adapt to social stimuli

by  /  22 April 2009

The characteristic inability of a person with autism to respond to emotions may stem from sustained arousal in the amygdala, the brain region needed to interpret emotions from facial expressions.

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March 2009

Raphael Bernier: Decoding the mysteries of the autistic brain

by  /  16 March 2009

In the spring of 2002, as a new graduate student at the University of Washington, Raphael Bernier was charged with introducing his advisor, Geraldine Dawson, before her lecture to a room of about 40 people from the psychology department. To Dawson’s astonishment, Bernier sang his introduction to the tune of On Top of Old Smokey. “[It was] a pretty gutsy thing for a first-year student to do,” Dawson says.

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February 2009

Daniel Geschwind: After many detours, on the trail of autism’s genetics

by  /  17 February 2009

In the late 1990s, after Daniel Geschwind had established himself as an expert on the genetics of neurological diseases, a personal connection abruptly pulled him into autism research. Since then, he has participated in dozens of studies probing the genetic basis of autism and related neuro-developmental disorders.

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January 2009

Rebecca Saxe: Fine tuning the theory of mind

by  /  26 January 2009

Rebecca Saxe has been designing brain imaging experiments to study infant brain development, moral judgment and theory of mind in people with autism, who often have trouble grasping othersʼ thoughts.

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The 2003 paper linking neuroligins to autism

by ,  /  12 January 2009

In 2003, Stephane Jamain and his colleagues reached a breakthrough by taking a candidate approach to the X chromosome, and linking members of the neuroligin protein family to autism.

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November 2008

A drug that lasts for days

by  /  19 November 2008

A new slow-release form of the drug risperidone ― an antipsychotic given to people with schizophrenia, autism and other psychiatric conditions ― lasts in the blood days instead of hours, according to research presented today at the Society for Neuroscience meeting.

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