Researchers probe genetic overlap between ADHD, autism
Attention deficit hyperactivity disorder (ADHD) and autism may have more in common than childhood onset and a few similar symptoms. New research suggests the conditions share genetic roots.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Attention deficit hyperactivity disorder (ADHD) and autism may have more in common than childhood onset and a few similar symptoms. New research suggests the conditions share genetic roots.
Several studies in the past year in people, mice and honeybees have tied autism to a protein that helps neurons communicate. Problems with the protein, neurexin 1, are associated with a wide range of autistic behaviors, such as impaired social interactions, anxiety and problems with learning and memory.
On 7 April, a group of investigators conducting autism genome sequencing projects met at the New York Academy of Medicine, aiming to establish the ground rules for a potential Autism Sequencing Consortium.
To examine protein interactions inside brain cells, scientists typically zero in on one gene at a time. A new method described in today’s Nature simultaneously measures expression of the whole genome.
Random changes in gene expression can cause genetically identical embryos to develop different traits, according to a study of worms published in Nature. The findings suggest that haphazard movements of molecules could partly explain why autism-associated mutations don’t always cause the same symptoms.
Writing in Science, leading scientists call for a 10-year, $2 billion international scheme that would combine the latest in genetics and animal research to combat psychiatric diseases.
The protein that is mutated in Rett syndrome controls the expression of other genes by changing the way DNA packs into a cell, rather than turning genes on or off, according to a study published in Molecular Cell.
The human brain holds a mind-boggling 100 billion neurons. Mapping their connections is the lofty goal of the Human Connectome Project, a $30 million scheme sponsored by the National Institutes of Health.
This summer will mark ten years since scientists sequenced the human genome. What have we gained from knowing those 3 billion base pairs?