A comprehensive atlas of gene expression by brain region could spur new research on autism.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.
Mice missing an autism gene called SHANK3 tend to be hypersensitive to touch, which may stem from underactivity of neurons that normally dampen sensory responses.
Even as a small child, geneticist Elise Robinson wondered why people think the way they do. Today, that question informs much of her autism research.
Researchers have cataloged more than 100 mutations in DDX3X, a candidate gene for autism.
People with mutations in a gene called TBR1 have unusual features in several brain regions, along with autism traits and developmental delay.
Lowering the levels of a protein called tau, best known for its involvement in Alzheimer’s disease, improves behavior in two mouse models of autism.
Rare mutations in a gene called BAZ2B are associated with various conditions of brain development, including autism.
Deletions and duplications of long stretches of DNA may increase the likelihood of autism in people who have a mutation in a gene called PTEN.
A new technique detects rare mutations that occur in only a subset of the body’s cells.