Genes tied to autism, developmental delay, schizophrenia share functions
Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.
The largest-yet study of genetic data from autistic people has identified 255 genes associated with the condition.
Researchers have rated more than 17,000 genes, including many linked to autism and other neuropsychiatric conditions, according to their sensitivity to deletions and duplications.
A novel method to evaluate the strength of the evidence linking autism to specific genes could reveal which ones are most useful to screen for.
Deleting CHD8 from the intestines induces gastrointestinal and behavioral changes in mice that resemble traits in people with mutations in the gene.
The investigational drug arbaclofen may right an imbalance between inhibitory and excitatory signaling in the animals’ brains.
Girls and women with mutations in the autism-linked gene DDX3X may be particularly vulnerable to anxiety and self-harm.
A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.
A technique that expands tissue before spotting and sequencing RNA — the molecular messenger for DNA — enables researchers to see where particular genes are expressed in cells.