Six strains of mice lacking a gene associated with fragile X syndrome show radically different behaviors though they share the same mutation, researchers reported in January in Autism Research.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
A partial mutation that leads to a milder form of fragile X syndrome causes deficits in learning and memory in mice, and alters the connections between their neurons, according to a study published in January in Neurobiology of Disease.
Two new studies of families carrying glitches on a region of chromosome 16, which has been strongly associated with autism, reveal the wide range of effects caused by the variant and narrow the list of possible culprit genes.
A genome-wide association study has identified risk factors for Asperger syndrome, some of which overlap with chromosomal regions implicated in autism, according to a study in the December issue of Autism Research.
Men with fragile X syndrome have larger brains overall than controls do, but less matter in regions involved in language and social interaction.
One of the first large-scale, ongoing studies documenting the symptoms of Angelman syndrome — a neurological disorder with features similar to autism — is calling into question some of the so-called characteristic symptoms of the syndrome.
A rare childhood speech disorder related to social anxiety is associated with a gene linked to autism, according to a study published in December in Biological Psychiatry. The results suggest that the two disorders share a common mechanism.