Skip to main content

Spectrum: Autism Research News

topic /

Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

November 2011

Video: What is the fragile X protein’s role in a neuron?

by  /  15 November 2011

The fragile X protein FMRP helps make proteins at the synapse, the junction between neurons, even when the genetic instructions for doing so are located far away in the nucleus, says Kimberly Huber.

Comments

Meta-analysis refines understanding of brain function

by  /  15 November 2011

Scientists are analyzing more than 7,000 studies of functional magnetic resonance imaging to refine the role of various regions in the brain, according to unpublished work presented Monday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

Different doses of Rett protein produce similar effects

by  /  15 November 2011

Mice that have an excess of the Rett syndrome protein MeCP2 have biochemical and neuronal characteristics that are strikingly similar to those of mice that completely lack the protein, according to unpublished research described Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

Genetics: Middle East study tags intellectual disability genes

by  /  15 November 2011

By focusing on recessive mutations inherited from both parents, researchers have identified 50 new candidate genes for intellectual disability.

Comments

Schizophrenia deletion could rouse silent mutations

by  /  14 November 2011

Deletion of 22q11, a schizophrenia-associated chromosomal region, may activate previously silent mutations, according to unpublished work presented Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

New approach mines multiple sources to link genes to disease

by  /  14 November 2011

Researchers have developed a computational technique that allows them to simultaneously use multiple types of information — including gene expression, ratings and associations — to identify candidate genes for a disorder. The unpublished results were presented Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

Researchers debut SHANK2 mouse, SHANK3 rat

by  /  14 November 2011

Mice lacking the autism risk gene SHANK2 show social deficits and are extremely hyperactive, according to unpublished research presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

Video: A landscape view of DNA modifications

by  /  14 November 2011

In a video interview at the 2011 Society for Neuroscience annual meeting in Washington, D.C., Janine LaSalle makes a case for the importance of the methylome in autism research.

Comments

Subset of Rett gene’s targets may lead to the disorder

by  /  14 November 2011

Deleting the Rett syndrome gene in a subset of neurons, instead of throughout the body, dramatically lowers the number of genes that are dysregulated in those neurons, according to results presented in a poster session Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments

Autism-linked protein plays role in zebra finch song

by  /  14 November 2011

Male zebra finches have high levels of contactin associated protein-like 2 (CNTNAP2), a protein that has been linked to autism and language disorders, in a key song-related area of their brains, according to unpublished research presented in a poster session Sunday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.

Comments