Molecular mechanisms: Fragile X drugs could treat autism
Postmortem brains from adults with autism have lower-than-normal levels of the fragile X mental retardation protein, which is missing in individuals with fragile X syndrome.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Postmortem brains from adults with autism have lower-than-normal levels of the fragile X mental retardation protein, which is missing in individuals with fragile X syndrome.
A well-studied mouse model of autism has a smaller-than-normal volume in several autism-associated brain regions.
A five-minute online questionnaire can diagnose autism with as much accuracy as the so-called gold standard diagnostic tests, according to unpublished findings presented Tuesday at the Autism Consortium 2011 symposium in Boston.
A massive association study links five new genetic regions to schizophrenia and implicates MIR137, a regulatory RNA that plays a role in neuron development, in the disorder.
In families that have more than one child with autism, the middle children, particularly those born second, have a higher risk of developing autism than other children in the family, according to a study published 19 October in PLoS One. In families that have only one child with autism, however, risk of the disorder rises with each additional birth, the study found.
A new study describes a mutant mouse that, despite missing an autism-linked gene, doesn’t show any autism-like behaviors.
An autism-linked protein helps wire neurons together, according to two studies published in late September.
Boys with autism have a distinct facial structure that differs from that of typically developing controls, according to a study published 14 October in Molecular Autism.
Stem cells reprogrammed to become neurons can provide a picture of gene expression in neurons that is traditionally available only from brain tissue.
Mice lacking a copy of SHANK3, a gene associated with autism and intellectual disability, show marked improvements in brain signaling after being treated with insulin-like growth factor 1, according to unpublished findings presented Saturday at the International Congress of Human Genetics in Montreal, Canada.