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Spectrum: Autism Research News

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Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

January 2012

Video technique measures monkeys’ social interest

by  /  11 January 2012

Male rhesus macaques show more interest in videos with social content, such as another monkey displaying aggression, than in videos of landscapes or other animals, according to a study published 26 October in PLoS One.

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A family on a walk.

Clinical research: Autism threshold higher in girls than boys

by  /  11 January 2012

Girls may have a higher threshold for the genetic abnormalities that lead to autism than boys do, according to a new study in the January issue of the American Journal of Medical Genetics Part B.  

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The value of blood cells in autism research

by  /  10 January 2012

Blood from individuals with autism could help researchers identify biomarkers to diagnose the disorder and learn more about related symptoms, such as gastrointestinal complaints, says molecular biologist Valerie Hu.

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Genetics: Large variants linked to intellectual disability

by  /  10 January 2012

Intellectual disability is more likely to be associated with multiple, large or non-inherited duplications and deletions of DNA than is autism, according to a study published 7 November in PLoS Genetics.

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Funding fears prevent researchers from sharing their mice

by  /  9 January 2012

Despite funders’ requirements to share mouse models after publication, many researchers hoard the animals for the good of their labs — and that could have an adverse effect on the field as a whole.

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Clinical research: Twin study links low birth weight to autism

by  /  6 January 2012

When twins differ in their diagnosis of autism, the twin with the lower birth weight is about three times more likely to develop the disorder than his or her sibling, according to a study published in the December issue of Psychological Medicine.

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To make big data available to all, reach for the clouds

by  /  5 January 2012

As the amount of genomics and other data rapidly grows, researchers are turning to cloud computing; commercial services for remote data storage and processing that allow even those with little infrastructure to handle big data.

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Brain atlas maps gene expression across development

by  /  4 January 2012

Researchers have charted the expression of more than 15,000 brain genes across 15 stages of development, spanning from 4 weeks post-conception to more than 60 years of age, they reported 27 October in Nature.

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Molecular mechanisms: Alzheimer’s protein linked to fragile X

by  /  4 January 2012

Lowering the levels of a protein associated with Alzheimer’s disease can rescue symptoms of fragile X syndrome in mice, according to a study published 26 October in PLoS One.

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Research evolution

by  /  3 January 2012

A new study examining trends in autism research over the past 40 years found that the largest areas of growth have been in immune function, oxidative stress, toxin exposure, genetics and neuroimaging, while research on theory of mind and neuropathology has slowed.

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