Lithium alleviates the symptoms of fragile X syndrome in mice in part by normalizing protein synthesis in the brain, according to a study published 29 December in Neurobiology of Disease.

A mathematical approach called ‘NEW biology,’ or network-enabled wisdom biology, aims to solve one of the biggest problems in disease research: isolating the key factors that drive diseases from a glut of information.

An automated instrument can reconstruct fluorescently labeled mouse brains in less than a day, researchers reported 15 January in Nature Methods.

Two compounds that enhance the activity of BDNF, a protein needed for the growth of neurons, improve motor skills in mouse models of Rett syndrome and increase the mice’s lifespan.

The results of two new studies support recommendations against the use of brain scans to diagnose autism.

Researchers have identified the genetic root of severe mitochondrial disorders in infants whose cases couldn’t be solved by standard genetic testing, according to research published last week in Science Translational Medicine.

A new study uses data from more than 10,000 typical individuals to validate candidate regions implicated in schizophrenia.

Researchers have mapped the levels of tiny RNA fragments that regulate gene expression in specific brain regions and subtypes of neurons. The results were published 12 January in Neuron.  

The genome-wide association study has been the favorite whipping post among some geneticists, but three new reviews come to its defense.

Neurobeachin, or NBEA, an autism–associated gene, may regulate the transport of signaling molecules to neuronal branches, according to a study published 22 November in Nature Communications.