Female mice missing a copy of the autism-linked gene MECP2 in a specific set of inhibitory neurons have a hard time heeding pups’ calls and herding litters.

Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.

People and mice with only one working copy of the autism gene SYNGAP1 may have trouble processing sights and sounds.

Treatments for Rett syndrome that aim to boost levels of the protein MECP2 may not help everyone with the condition.

Mice missing one copy of the autism-linked gene DDX3X have smaller brains and worse motor skills than mice with both copies of the gene, according to a new unpublished study.

Deleting the autism-linked gene CNTNAP2 from mice leads to distinct cellular and electrical changes in the cerebellum, according to two unpublished studies presented virtually today at the 2021 Society for Neuroscience Global Connectome.

Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.

Mutations in the autism-linked gene ASH1L change how neurons grow and develop.

Mutations seen in only some of the body’s cells often affect gene activity in the brains of people with autism, and can involve large segments of DNA, according to two new studies.

Mice missing a copy of the autism-linked gene NRXN1 appear to perceive some time intervals as shorter than control mice do, according to a new study.