Genes

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

Neurons derived from autistic people with enlarged brains show extensive damage to long genes.

Mice missing a copy of CHD8, a top autism gene, show a signaling imbalance in their brains — a finding in line with a popular hypothesis about autism’s origins.

A new method uses mutations in DNA to maintain a detailed record of series of cellular events.

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

A molecule made by mitochondria, the energy factories of cells, might help doctors forecast the impact of mutations in a top autism gene.

The largest analysis of sequences from autistic people and their families implicates 184 genes in the condition — nearly doubling the previous estimate.

SETD5, a leading candidate for autism risk, may control thousands of genes by modifying a protein involved in packaging DNA.

Deleting the mutation from an autism gene may reverse some autism traits in mice, according to a new study. But the results may be a fluke.