TOPIC

Environment

From parental age to infection during pregnancy, environmental elements can influence autism risk.

June 2011
News

Molecular mechanisms: Metabolic changes increase risk of autism

by  /  8 June 2011

Children with autism have fewer DNA modifications that regulate gene expression compared with healthy siblings and controls, and show evidence of DNA damage, according to a study published 26 April in the Journal of Autism and Developmental Disorders.

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Opinion / Viewpoint

Solving the complex causes of a multi-hit disorder

by ,  /  7 June 2011

What’s known about the genetics of autism supports the ‘snowflake’ hypothesis — that the molecular underpinnings of disease are essentially unique from individual to individual — says human geneticist Brett Abrahams.

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Opinion

Information overload

by  /  3 June 2011

Sensory sensitivity is one of the most understudied aspects of autism. That’s a serious problem, because it underlies much of the distress experienced by people with the disorder, says best-selling author and animal scientist Temple Grandin.

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News

Clinical research: Autism rates in adults higher than suspected

by  /  1 June 2011

A large population survey in England finds many adults with undiagnosed autism, bringing the disorder’s prevalence in adults to 1 in 100, approximately the same rate as in children, according to a report in May in the Archives of General Psychiatry.

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May 2011
News

Molecular mechanisms: Placenta influences brain development

by  /  31 May 2011

The placenta regulates the levels of the neurotransmitter serotonin in the brains of mice at a key stage in embryonic development, according to a study published 21 April in Nature. The results suggest that the fetal environment can influence the long-term mental health of children, including whether they later develop autism or schizophrenia.

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News

Networks of genes altered in autism brains, study says

by  /  25 May 2011

Two networks of genes are abnormally expressed in the brains of people with autism, according to a study published today in Nature.

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Opinion

Seeking a cure

by  /  17 May 2011

Parents of children with autism choose treatment options based on what they believe caused the disorder, according to a French study. More education about autism could help them make better choices.

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News

Family sequencing study boosts two-hit model of autism

by  /  15 May 2011

A new analysis of children with autism and their unaffected parents provides the best evidence to date that mutations in multiple genes may work together to cause autism and related disorders.

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News

Scientists probe puzzling overlap of epilepsy and autism

by  /  12 May 2011

Large studies on the epidemiology and genetics of epilepsy and autism have uncovered commonalities between the two disorders. But scientists are only beginning to untangle the biological roots of the overlap.

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News

Clinical research: Studies add to confusion over gut-autism link

by  /  11 May 2011

People who have severe gastrointestinal problems during childhood are no more likely to be on the autism spectrum than are healthy controls, a study reported 21 March in Developmental Medicine and Child Neurology.

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