Children with autism carry twice as many new and damaging genetic mutations as typically developing children, according to a new study published in Neuron. The researchers also identified intriguing genetic links between autism and fragile X syndrome.

Individuals with autism may belong to one of four groups with discrete sets of symptoms, the most distinct of which includes immune system abnormalities accompanied by sleep problems and sensory sensitivity. The results were published in the April issue of Autism Research.

Mutant mice with autism-like behaviors have fewer behavioral impairments when provided with toys, exercise wheels and contact with other mice, than do those that live in typical laboratory cages, according to a study published 5 April in Human Molecular Genetics. 

A new study, published in the journal Pediatrics, made headlines this week by suggesting that motherhood obesity may increase the risk of autism in children.

Both premature and post-term babies develop more severe symptoms of autism than those born close to their due dates, according to a study published 16 March in the Journal of Autism and Developmental Disorders.

The largest set of exome sequencing studies of children with autism and their families to date has identified a handful of genes that may increase risk of the disorder, according to research published in Nature.

Full siblings are twice as likely as half siblings to share a diagnosis of autism, according to a short report published 28 February in Molecular Psychiatry. The results suggest that genetic factors play an important role in the risk of developing autism, the researchers say.

Molecules generated by an immune reaction in pregnant rats affect the brains of their offspring, leading to changes in gene expression, according to a study published 30 January in Brain, Behavior and Immunity.

A bone marrow transplant from healthy mice to those lacking the MeCP2 protein, which causes Rett syndrome, extends lifespan and alleviates symptoms of the disorder, according to research published online 18 March in Nature.

A new study suggests that children with both autism and gastrointestinal disorders have poorer language and social skills than those with autism alone.