Understanding the interactions between the placenta and the uterine lining could explain how maternal immune activation leads to autism.
From parental age to infection during pregnancy, environmental elements can influence autism risk.
A cell atlas and a cell-culture method promise to advance scientists’ understanding of the placenta and its effects on a fetus.
Consuming Lactobacillus reuteri, a gut microbe found in yogurt and breast milk, may enhance social interactions in three mouse models of autism.
Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.
Chronic exposure to inflammation in the womb alters autism gene expression and disrupts social behavior in male mice, but not females.
Rats exposed prenatally to a cocktail of ‘autoimmune’ molecules have altered levels of two types of compounds needed for brain development.
A specially made ‘decoy’ protein prevents an immune molecule from crossing the placenta; the strategy may prevent the brain changes that lead to autism.