TOPIC

Environment

From parental age to infection during pregnancy, environmental elements can influence autism risk.

December 2014
Opinion / Viewpoint

Future of autism genetics should learn from its past

by  /  9 December 2014

To optimize the search for autism genes, researchers should collect large numbers of sequences — but the sequences need to be of the right kind, says Michael Ronemus.

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November 2014
Features / Deep Dive

Genetics first: A fresh take on autism’s diversity

by  /  24 November 2014

Each child with autism is different from the next. One approach rapidly gaining momentum makes sense of this diversity by grouping children together based on their genetics, then looking for patterns in their symptoms. The long-term aim: personalized treatments for each subtype of autism.

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Opinion

Mouse study sheds light on maternal infection, autism link

by  /  21 November 2014

A new study points to a possible link between inflammation in the womb, brain overgrowth and the behavioral impairments seen in autism.
 

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News

Enriched environment staves off autism-like behavior in rats

by  /  20 November 2014

Rats exposed in utero to the epilepsy drug valproic acid, a risk factor for autism, do not develop autism-like behaviors if they are reared in a stimulating environment. Researchers presented the unpublished findings yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

In mouse model of Rett, immune cells overly sensitive

by  /  20 November 2014

Loss of MeCP2, the Rett syndrome gene, depletes immune cells throughout the bodies of mice, researchers reported yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Mutation boosts paternal age’s autism-like effects in mice

by  /  19 November 2014

Mice born to older males with mutations in PAX6 — a gene involved in brain development — vocalize less than those with younger dads. The unpublished findings, presented today at the 2014 Society for Neuroscience annual meeting in Washington, D.C., suggest how genes and paternal age can work together to trigger symptoms.

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News

Fond caresses, loving squeezes shape social brain

by  /  19 November 2014

Soft touch and physical closeness to other people wire the social brain right from the earliest days after birth, and problems in the response to touch may play a fundamental role in autism. This picture emerges from unpublished results presented by several teams at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Cesarean birth alters immune system, social behavior in mice

by  /  18 November 2014

Mice born via cesarean section show subtle social deficits and increased immune and stress responses, suggesting a link between microbe exposure during birth and behavior. Researchers presented the unpublished work today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Strep infection in pregnant rats causes autism features in pups

by  /  18 November 2014

Infection with group B streptococcus bacteria in pregnant rats triggers brain abnormalities and autism-like behaviors in their pups — especially in males. Researchers presented the unpublished results today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Tadpole model links epilepsy drug’s effects to chromatin

by  /  16 November 2014

Valproic acid, an epilepsy drug that increases the risk of autism, may alter neural circuits by opening up chromatin, a tightly packaged form of DNA in the nucleus. Researchers presented the unpublished data today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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