Rare mutations that increase the risk of neuro-psychiatric diseases usually occur in only one copy of a gene. What happens when both copies are mutated?
Diagnosing autism is an evolving science but a crucial first step to understanding the disorder.
Genetic analysis of one Belgian family with a history of autism has pinpointed a piece of DNA on chromosome 16, within a segment thought to be missing in about one percent of all cases of autism. The unpublished data was presented on Saturday at the World Congress of Psychiatric Genetics in San Diego.
A pathway involved in language development is increasingly proving to be important in autism, suggest a series of new studies on cellular and behavioral aspects of the disorder.
A team of British researchers has garnered some of the first genetic evidence supporting their theory that sex hormones play a role in the development of autism.
People with Asperger syndrome don’t automatically show ‘theory of mind’, the ability to understand the desires and beliefs of others, according to a report published 16 July in Science. Instead, they seem to use deliberate reasoning to understand social behaviors, learned after years of practice in the real world.
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In the late 1990s, after Daniel Geschwind had established himself as an expert on the genetics of neurological diseases, a personal connection abruptly pulled him into autism research. Since then, he has participated in dozens of studies probing the genetic basis of autism and related neuro-developmental disorders.