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Spectrum: Autism Research News

Tag: whole-genome sequencing

September 2016

Mutations tied to autism rife in ‘junk’ DNA

by  /  9 September 2016

More than one-third of the spontaneous mutations linked to autism crop up in genomic segments that do not code for genes.

April 2016

Webinar: Brian O’Roak discusses the accelerating pace of autism genetics

 /  27 April 2016

Watch the complete replay of Brian O’Roak discussing the accelerating pace of autism genetics and new methods for identifying and validating autism risk genes.


DNA flips and swaps ‘scramble’ genes linked to autism

by  /  14 April 2016

Most methods used to scan the genome are missing thousands of complex variants that alter DNA structure and may contribute to autism risk.


How to mine treasure troves of genetic data

by  /  5 April 2016

Collaboration and transparency will be key as scientists sort through thousands of whole genomes of people with autism for genetic clues.

March 2016

Method maps each neuron’s unique genetic fingerprint

by  /  23 March 2016

Sequencing the whole genomes of individual mouse neurons reveals that each cell carries roughly 100 unique mutations.


Questions for Thomas Bourgeron: In search of ‘second hits’

by  /  1 March 2016

Taking a close look at people who have a mutation in a known autism gene may reveal why these people often have vastly different characteristics.

February 2016

Spaces near genes may harbor pitfalls for autism

by  /  15 February 2016

Children with autism tend to carry variants in stretches of DNA that flank autism genes.

December 2015

Hot topics of 2015

by  /  22 December 2015

Here’s a rundown of five trending topics that are turning traditional assumptions about autism on their head.


U.S. aims to overhaul ethics rules for research with people

by  /  17 December 2015

The proposed guidelines would require scientists to destroy biological specimens if they don’t have the explicit consent of the participant for further use.

November 2015

Long-awaited databases reveal breadth of genetic variation

by  /  4 November 2015

Two massive efforts to sequence the DNA of more than 11,000 people together provide the most detailed picture yet of genetic variation in the general population.