A new chart of DNA’s three-dimensional structure reveals genomic regions that control distant genes during development.
Spectrum: Autism Research News
Tag: whole-genome sequencing
Watch the complete replay of Brian O’Roak discussing the accelerating pace of autism genetics and new methods for identifying and validating autism risk genes.
Most methods used to scan the genome are missing thousands of complex variants that alter DNA structure and may contribute to autism risk.
Sequencing the whole genomes of individual mouse neurons reveals that each cell carries roughly 100 unique mutations.
Taking a close look at people who have a mutation in a known autism gene may reveal why these people often have vastly different characteristics.