Peer review panels really can suss out good science, and clinical trials could get extremely personal.

Watch the complete replay of Kathryn Roeder’s webinar discussing how powerful statistical tools can yield insight into the genetic risk for autism.

Some newborn horses have features of autism, and researchers argue over who first described the disorder.

Less than one-third of sibling pairs with autism who carry rare mutations in autism-linked genes share those mutations, according to the largest study yet to sequence whole genomes of people with the disorder. The study questions the assumption that autism’s risk factors run in families, but some experts are skeptical.

A new method is faster and more accurate than previous methods at revealing the complex folds that help to fit nearly six feet of DNA into the tiny nucleus of a cell.

By analyzing stem cells derived from baby teeth, researchers have tracked a child’s autism to mutations in a gene called TRPC6. The molecular saga highlights a painless way to probe the role some genes play in autism.

A new computational approach predicts how sequence variations in both the coding and noncoding regions of a gene affect the gene’s expression. The method, described today in Science, may help researchers understand how specific variants contribute to disorders such as autism.

Getting to a diagnosis of autism or another neurodevelopmental disorder is a long and frustrating experience for some families — especially when it comes to finding the underlying genetic cause. DNA sequencing could ease this arduous journey.

To optimize the search for autism genes, researchers should collect large numbers of sequences — but the sequences need to be of the right kind, says Michael Ronemus.

A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.