The number of top autism genes has risen from 65 to 99, based on an analysis of nearly 35,000 sequences. And researchers are seeing the first hints of autism risk variants in the regions between genes.
To find variants between genes that contribute to autism, researchers may need thousands more whole genomes than they have now.
The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.
A new analysis of the genomes of more than 11,000 people reveals regions that have few mutations, indicating they have important functions.
Some children with autism inherit rare mutations in noncoding DNA from their unaffected fathers.
A single gene, OTUD7A, may account for most of the features seen in people missing a segment of chromosome 15 known as 15q13.3.
More than 5 percent of mutations thought to have arisen spontaneously in a child with autism may in fact be inherited.
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