Children with autism tend to carry variants in stretches of DNA that flank autism genes.
Brian O’Roak has helped to steer some of the largest, most complex studies of autism genetics to date.
Two massive efforts to sequence the DNA of more than 11,000 people together provide the most detailed picture yet of genetic variation in the general population.
Analyzing thousands of sequences, researchers have homed in on miniscule portions of the genome that may be crucial in determining autism risk.
Researchers in Sweden are assembling a large group of identical twin pairs, with only one twin in each pair having autism.
Two studies prioritize autism risk genes for further research and illuminate how different types of mutations may work together.
Combining two genetic tests with a physical exam may flag young children at risk for autism years earlier than behavioral assessments do.