Tag: UBE3A

November 2010
News

Molecular mechanisms: Angelman gene linked to synapse formation

by  /  16 November 2010

UBE3A, a protein mutated in Angelman syndrome and autism, regulates communication between neurons in the brain, according to a study published 29 October in Cell.

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October 2010
News

Multi-gene deletion creates model for Angelman syndrome

by  /  7 October 2010

A new mouse model of Angelman syndrome that knocks out a large stretch of a key chromosome is clarifying some of the molecular mechanisms underlying the more severe forms of the disorder.

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April 2010
News

Scientists find molecular player in Angelman syndrome

by  /  27 April 2010

Two independent teams have discovered key molecular steps in the way a single gene disrupts the connections between neurons in individuals with Angelman syndrome. Because the gene, UBE3A, has also been linked to autism, the findings could help scientists understand and treat a range of neurodevelopmental disorders.

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December 2009
News

Chemical messenger variant found in families with autism

by  /  16 December 2009

Scientists have for the first time found direct evidence that defects in the GABA receptor sometimes give rise to autism, according to research published 24 November in Molecular Psychiatry.

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November 2008
News

A simple behavioral test for mice

by  /  17 November 2008

Researchers at the Society for Neuroscience today described a new test for animal behavior that doesn’t interfere with normal mouse behavior, doesn’t require human interaction, and makes it simple to take long-term measurements: the ‘licking testʼ.

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