Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

Watch the complete replay of Shafali Jeste discussing her work investigating brain structure and function in infants at high risk for autism. 

A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.

Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.

A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

A surprising number of genes associated with autism also have links to cancer. Does that mean cancer drugs can treat autism?

Mutations in TSC2, a gene typically associated with a syndrome called tuberous sclerosis, are found in many children with autism.

A treatment that targets the genetic defect in tuberous sclerosis prevents autism-like symptoms in mice at 6 weeks of age — the mouse equivalent of adolescence. Researchers presented the unpublished results yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.