Tag: TSC2

August 2019
News

Trial results temper hopes of tumor drug for treating autism

by  /  29 August 2019

A drug that treats tumors and epilepsy in people with tuberous sclerosis complex does not boost their intelligence or ease autism traits.

0 Comments
November 2018
Two white mice, one on a wheel, sniff noses.
News

Infection during childhood may aggravate autism risk from mutation

by  /  7 November 2018

Triggering an immune defense in newborn male mice missing a copy of TSC2, a gene linked to autism, impairs the mice’s social memory.

0 Comments
August 2018
Two scientists standing in a lab.
News / Profiles

Family ties: Sabatini brothers crack codes that may underlie autism

by  /  30 August 2018

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

0 Comments
April 2018
Multimedia / Webinars

Webinar: Shafali Jeste discusses brain development in high-risk infants

25 April 2018

Watch the complete replay of Shafali Jeste discussing her work investigating brain structure and function in infants at high risk for autism. 

0 Comments
Week of AprilApr
9th
2018
News / Spotted

Fragile X checklist; France plays catch-up; bar-coded neurons and more

by  /  13 April 2018

A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.

0 Comments
March 2018
A mouse model of tuberous sclerosis (right) shows less protein synthesis in the brain than a control (left).
News

Shortage of proteins upends theory of tuberous sclerosis origins

by  /  14 March 2018

Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.

0 Comments
November 2017
Mice missing the tuberous sclerosis gene in astrocytes have frequent seizures.
News

Cancer drug wards off seizures in mouse model of tuberous sclerosis

by  /  13 November 2017

A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.

2 Comments
September 2017
Illustration of Protein factories at neuronal junctions
Opinion / Viewpoint

Protein factories at neuronal junctions take center stage in autism

by ,  /  12 September 2017

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

0 Comments
January 2017
Features / Deep Dive

The curious connection between autism and cancer

by  /  11 January 2017

A surprising number of genes associated with autism also have links to cancer. Does that mean cancer drugs can treat autism?

0 Comments
May 2016
News

Mutations in tuberous sclerosis gene may be rife in autism

by  /  14 May 2016

Mutations in TSC2, a gene typically associated with a syndrome called tuberous sclerosis, are found in many children with autism.

0 Comments