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Spectrum: Autism Research News

Tag: TSC1

April 2018

Webinar: Shafali Jeste discusses brain development in high-risk infants

 /  25 April 2018

Watch the complete replay of Shafali Jeste discussing her work investigating brain structure and function in infants at high risk for autism. 

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Week of AprilApr
9th
2018

Fragile X checklist; France plays catch-up; bar-coded neurons and more

by  /  13 April 2018

A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.

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March 2018
A mouse model of tuberous sclerosis (right) shows less protein synthesis in the brain than a control (left).

Shortage of proteins upends theory of tuberous sclerosis origins

by  /  14 March 2018

Mice with the mutations linked to tuberous sclerosis make too little protein in their brains — a finding that contradicts a leading theory about the condition.

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December 2017
four brains with the RCrusl section highlighted

Study of cerebellum’s role in autism homes in on ‘social’ region

by  /  18 December 2017

New evidence from both people and mice points to a part of the cerebellum that helps process social information as being critical in autism.

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November 2017
Mice missing the tuberous sclerosis gene in astrocytes have frequent seizures.

Cancer drug wards off seizures in mouse model of tuberous sclerosis

by  /  13 November 2017

A drug called rapamycin prevents seizures in a mouse model of the autism-related condition tuberous sclerosis complex.

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closed eye and wide open eye against sky

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

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September 2017
Illustration of Protein factories at neuronal junctions

Protein factories at neuronal junctions take center stage in autism

by ,  /  12 September 2017

Some genes linked to autism regulate the production of proteins at neuronal junctions, suggesting that disrupted protein synthesis contributes to the condition.

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January 2017

Exploring the hidden world of inhibitory brain signals

by ,  /  24 January 2017

Scientists have discovered more than 100 new proteins at junctions in the brain that dampen neuronal activity.

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A surreal portrait of doctors walking out on vibrant tree-limbs, as it were. This represents doctors exploring novel pathways in cancer research.

The curious connection between autism and cancer

by  /  11 January 2017

A surprising number of genes associated with autism also have links to cancer. Does that mean cancer drugs can treat autism?

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August 2015

Blinking mice bolster cerebellum’s link to autism

by  /  14 August 2015

Mice carrying any one of five autism-linked mutations struggle to associate a flash of light with an irritating puff of air. The findings suggest that the mice have trouble integrating information from multiple senses — a skill governed by the cerebellum.

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