The cloudy connection between fragile X and cancer
People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies.
People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies.
The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.
Sleep problems may contribute to or derive from autism traits — or both. After decades of work, researchers are beginning to uncover the biological connections between the two conditions, revealing new paths to potential treatments.
Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Long known as the director of movement, the cerebellum may also coordinate social and cognitive abilities, including those central to autism.
Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.
A drug that treats tumors and epilepsy in people with tuberous sclerosis complex does not boost their intelligence or ease autism traits.
Two studies published in the past two months provide new clues to when and how the cerebellum contributes to autism.
David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.