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Spectrum: Autism Research News

Tag: Timothy syndrome

November 2010

Video: Why make neurons from children with autism?

by  /  19 November 2010

Ricardo Dolmetsch is making neurons from induced pluripotent stem cells derived from people with Timothy syndrome, a rare single-gene disorder that causes heart arrhythmias and autism. On Wednesday morning at the Society for Neuroscience annual meeting in San Diego, Dolmetsch talked to SFARI about how this approach could help autism research.

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Automated cage helps diagnose social behavior

by  /  18 November 2010

Researchers have designed an automated cage assay to minimize the anxiety mice feel as they are being tested for social behavior. The new technique was presented at the Society for Neuroscience annual meeting in San Diego.

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Mouse model of Timothy syndrome shows social deficits

by  /  15 November 2010

Mice bearing the genetic defect that causes Timothy syndrome show many autism-like behaviors, and may also have enhanced cognitive abilities like those seen in a small number of people with autism, suggests a poster presented Sunday at the Society for Neuroscience annual meeting in San Diego.

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Stem cells reveal neuroligin’s role in development

by  /  15 November 2010

Stem cell studies show that a mutation in the neuroligin-4 gene disrupts the normal development of synapses, the junction between neurons, according to unpublished data shown Sunday at the Society for Neuroscience annual meeting in San Diego.

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July 2009

New autism gene points to cellular calcium imbalance

by  /  14 July 2009

A common variant of a gene called CACNA1G — which makes a channel that helps regulate calcium flow between cells — may increase the risk of developing autism, according to research published in Molecular Psychiatry.

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November 2008

Creating stem cells to study autism

by  /  18 November 2008

A team of scientists is reprogramming adult stem cells generated from tiny skin samples of people with autism to form nerve cells, creating a powerful research tool for the disorder.

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