Tag: Timothy syndrome

June 2017
News / Toolbox

Mini-brains bare tortuous trek of cells in Timothy syndrome

by  /  23 June 2017

A new technique for building a ‘brain in a dish’ reveals how neurons move to their proper places during fetal development.

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April 2017
Opinion / Viewpoint

Mighty element plays major part in autism

by ,  /  18 April 2017

Probing the function of a protein in a calcium signaling pathway may lead to a diagnostic test for autism and a path toward treatments.

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February 2015
News / Profiles

Rising Star: Sergiu Pasca, scientist at play

by  /  19 February 2015

Sergiu Pasca was among the first to model autism with neurons from affected individuals, a feat that could reveal the biochemical roots of some forms of autism.

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March 2013
Opinion / Viewpoint

Rho family of enzymes at crossroads of autism

by  /  12 March 2013

A number of autism risk factors converge on one cellular pathway: abnormal remodeling of the cell’s structural systems through the signaling protein Rho, says SFARI’s associate director for research, Alan Packer.

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News

Molecular mechanisms: Timothy syndrome neurons defective

by  /  12 March 2013

Neurons from people with Timothy syndrome, and from mouse and rat models of the disorder, have defects in the growth of their branches, according to a study published 13 January in Nature Neuroscience.

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January 2013
Opinion / Viewpoint

Exploring enigmatic links between mitochondria and autism

by  /  8 January 2013

Mitochondrial deficits may account for the range of symptoms and neurological deficits seen in autism and explain why it preferentially affects boys, says Douglas Wallace.

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October 2012
News

Allen Institute aims to mass-produce stem cells

by  /  5 October 2012

The nonprofit Allen Institute for Brain Science in Seattle plans to make neurons from stem cells derived from people with a number of different disorders. The resource, described 25 September at a conference in New York, will be available to all scientists.

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August 2012
Opinion

Rodent roundup

by  /  10 August 2012

SAGE Labs has announced a new partnership with the autism science and advocacy organization Autism Speaks to fund the creation of three new rat models of autism.

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July 2012
Opinion / Viewpoint

Targeting brain microcircuits may help treat autism

by  /  10 July 2012

Understanding the function of neuronal circuits, specifically microcircuits in the prefrontal cortex and elsewhere in the brain, will play a major role in translating research findings into new autism treatments, says Vikaas Sohal.

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June 2012
Opinion / Q&A

Q&A with Luca Santarelli: Targeting neuronal connections

by  /  12 June 2012

Luca Santarelli, head of neuroscience at Roche, explains why he is optimistic that pharmaceutical companies can overcome the obstacles in autism drug development.

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