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Spectrum: Autism Research News

Tag: synaptic plasticity

January 2022

New method spotlights synaptic plasticity in living mice

by  /  5 January 2022

Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.

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November 2021

Dispatches from SfN 2021: Mitochondria, Rett therapy and oxytocin

These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.

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Fragile X theory falters on amygdala test

by  /  10 November 2021

Activating certain receptors in the amygdala — a treatment that runs counter to a leading theory of what causes the condition — can reverse some traits in rats.

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October 2021

Autism-linked gene SYNGAP1 molds synaptic plasticity, learning

by  /  21 October 2021

Even partial loss of the gene impairs the mouse brain’s ability to respond to sensory experiences, which may explain why people with SYNGAP1 mutations tend to have learning difficulties and a high pain tolerance.

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Black CDKL5 mice in a lab setting--three mice in a cage.

Brain stimulation improves memory in autism mouse models

by  /  15 October 2021

Jolting a bundle of nerve fibers deep in the brain restores learning and memory in mice with mutations of the autism-linked gene CDKL5.

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August 2021
Illustration of brain showing overexcited and underexcited parts of the brain represented by jagged and loose squiggles.

Disruptions to brain’s ‘thermostat’ may underpin autism traits

by  /  18 August 2021

Mounting evidence suggests that autism often involves upsets in homeostatic plasticity, a set of processes neurons use to stabilize their activity. These disruptions result from a range of autism-linked mutations and may help to explain the condition’s famed heterogeneity.

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March 2021
Scientists Damien Fair, Constance Hicks-Smith and Brian Boyd

Black autism researchers weigh in on field’s past, future

by  /  3 March 2021

Spectrum spoke with three Black scientists about why they got into autism research, what keeps them excited about their work and how the field could become more diverse.

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August 2020
Mouse brain images show proteins in mouse brains at different ages.

New ‘synaptome’ maps neuronal connections in mouse brain across lifespan

by  /  5 August 2020

A new atlas lays bare how synapses, or the junctions between neurons, change from birth to old age in mice.

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April 2020
Two neuron images compared side by side

Lithium may treat behavior linked to autism gene

by  /  24 April 2020

The mood-stabilizing drug lithium seems to ease repetitive behaviors seen in mice missing SHANK3, an autism gene.

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January 2019

Revelando los secretos del síndrome X frágil en Colombia

by  /  31 January 2019

Una remota ciudad colombiana es el hogar del grupo más grande de personas con síndrome de X frágil. Los científicos están aprendiendo de ellos y tratando de ayudar.

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