Testing gene therapy for autism in mice? Consider your controls
Deleting the mutation from an autism gene may reverse some autism traits in mice, according to a new study. But the results may be a fluke.
Deleting the mutation from an autism gene may reverse some autism traits in mice, according to a new study. But the results may be a fluke.
Sleep problems may contribute to autism’s underlying biology — a connection that scientists can study in animal models.
Two new maps show the entire nervous system of the adult roundworm Caenorhabditis elegans.
Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.
Brain tissues from people with autism of unknown cause and from people with either of two genetic forms of the condition all show similar patterns of methyl groups on DNA.
Two new resources may aid the study of synapses, the junctions between neurons.
Families of children with mutations in a gene called SYNGAP1 have spurred research into the effects of the mutations on people — and how to treat them.
Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.
Recent advances in technology allow researchers to measure RNA that is contained within the nucleus of a single brain cell.
A new technique leads to neuron cultures of consistent quality, enabling scientists to study how autism mutations alter neurons.