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Spectrum: Autism Research News

Tag: synapses

January 2021
grid of clocks showing different times

Missing autism gene may affect time perception in mice

by  /  11 January 2021

Mice missing a copy of the autism-linked gene NRXN1 appear to perceive some time intervals as shorter than control mice do, according to a new study.

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November 2020
SYNGAP1 protein between neurons.

Reactions from the 2020 SYNGAP1 Scientific Conference

by  /  25 November 2020

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

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August 2020
Mouse brain images show proteins in mouse brains at different ages.

New ‘synaptome’ maps neuronal connections in mouse brain across lifespan

by  /  5 August 2020

A new atlas lays bare how synapses, or the junctions between neurons, change from birth to old age in mice.

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May 2020

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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April 2020
Two neuron images compared side by side

Lithium may treat behavior linked to autism gene

by  /  24 April 2020

The mood-stabilizing drug lithium seems to ease repetitive behaviors seen in mice missing SHANK3, an autism gene.

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Microscopic view of neurons

Mutations in autism gene linked to distinct conditions

by  /  3 April 2020

Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.

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February 2020
3D image of colorized brain sections showing neuron connections

Map of fly brain lights up millions of connections

by  /  12 February 2020

A new wiring diagram of the fruit fly brain is the most complex ever created.

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November 2019
Micrograph of mouse brain showing transplanted human microglia

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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October 2019

CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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Signaling imbalance in mutant mice supports key autism theory

by  /  19 October 2019

Mice missing a copy of CHD8, a top autism gene, show a signaling imbalance in their brains — a finding in line with a popular hypothesis about autism’s origins.

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