Tag: synapses

December 2018
News

Massive analysis refines map of autism’s genetic roots

by  /  19 December 2018

The largest genetic analysis of postmortem brain tissue to date has yielded maps of when and where genes related to autism are turned on and off throughout life.

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November 2018
Black and white images shows human neurons grafted onto a mouse brain grow over time.
News / Toolbox

Human neurons take root in living mouse brains

by  /  30 November 2018

Neurons grown from human stem cells and grafted onto the brains of live mice mature and form connections like those in the fetal human brain.

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News

Top autism gene may rewire brain by altering expression of other genes

by  /  15 November 2018

The autism gene TBR1 controls the expression of several other candidate genes that govern the architecture of the brain’s outer section.

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News

Neuron tag may shield synapses from brain’s pruning shears

by  /  12 November 2018

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

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Neurons glow green in mice brain.
News

Loss of autism gene alters landscape of inhibitory brain signals

by  /  6 November 2018

Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.

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News

Inflammation in womb may spawn autism-like traits in males

by  /  6 November 2018

Chronic exposure to inflammation in the womb alters autism gene expression and disrupts social behavior in male mice, but not females.

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News

Mutations in autism gene may be treatable beyond infancy

by  /  4 November 2018

A top autism gene called SCN2A plays a role at neuronal connections into adulthood, offering hope for treating mutations after infancy.

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A 3D rendering shows a neuron firing on black.
News

Tweak cleans up ‘pollution’ in images of firing neurons

by  /  3 November 2018

Targeting a fluorescent protein to the cell bodies of neurons enables researchers to clearly see which neurons fire when.

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September 2018
Abnormalities in proteins at synapses are implicated in autism.
News

Billions of neuronal junctions make up new ‘synaptome’ map

by  /  20 September 2018

Researchers have charted billions of synapses in the mouse brain and sorted them by type.

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News

Loss of large proteins underlies fragile X syndrome, study says

by  /  13 September 2018

The protein missing in fragile X syndrome, FMRP, facilitates the production of hundreds of unusually large proteins, some of which are linked to autism.

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