Skip to main content

Tag: striatum

February 2017
News

Rats with mutant SHANK genes show autism-like behaviors

by  /  16 February 2017

Researchers have engineered two new rats with mutations in a family of genes that function at neuronal junctions, they reported today at the 2014 International Meeting for Autism Research in Atlanta.

0 Comments
November 2016
Mouse brain hippocampus
News

New mice expose consequences of key autism gene

by  /  17 November 2016

Mice with an extra copy of the autism risk gene UBE3A have cognitive deficits and anxiety, but do not show any core features of the condition.

0 Comments
August 2016
News / Toolbox

Maps reveal genetic landscape of developing monkey brain

by  /  12 August 2016

Researchers have charted gene expression in the brains of rhesus macaques from before birth into adulthood.

0 Comments
January 2016
News

Neighboring mutations in gene may spawn separate conditions

by  /  25 January 2016

Two seemingly similar mutations in the SHANK3 gene have divergent effects on the brain and behavior.

1 Comment
November 2015
News

Newly named player in gene expression may be key in autism

by  /  23 November 2015

A chemical tag on DNA that has risen to prominence only in the past few years is altered in people with autism, suggest results from an autism mouse model.

0 Comments
October 2015
News

For autism mouse models, gender matters

by  /  22 October 2015

The mutation that leads to Angelman syndrome may affect the brains of female mice more severely than those of male mice.

0 Comments
August 2015
News / Toolbox

Remote control for rodent behavior dispenses drugs

by  /  19 August 2015

A new device lets researchers wirelessly stimulate the brains of rodents as they explore their cages, and can deliver drugs at the same time. Its use could identify brain circuits that mediate autism-like behaviors.

0 Comments
June 2015
News / Toolbox

Atlas charts gene activity in developing monkey brains

by  /  10 June 2015

Researchers have for the first time mapped gene expression in the rhesus macaque brain from birth through adulthood. The atlas illuminates the expression patterns of genes likely to be important in autism.

0 Comments
February 2015
News

Gene networks offer entry point to unraveling autism

by  /  26 February 2015

By mapping the connections between autism genes, researchers are finding clues to the disorder’s origins. The key, they say, is to begin without bias.

8 Comments
November 2014
News

Family of autism-linked proteins helps neurons communicate

by  /  16 November 2014

The SHANK family of proteins, some of which are strong autism candidates, work together to facilitate brain signaling, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

0 Comments