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Spectrum: Autism Research News

Tag: striatum

January 2021
In cortical-striatal assembloids, striatal neurons (magenta) derived from individuals with Phelan-McDermid syndrome fire more frequently than neurons from controls.

Brain ‘assembloids’ capture circuit flaws in syndrome tied to autism

by  /  21 January 2021

Merging 3D clusters of neurons that mimic different brain regions models the atypical electrical activity seen in an autism-related condition.

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December 2020
researcher facing off with the coronavirus.

Rewind: Spectrum’s best from 2020

by  /  23 December 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

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October 2020
Illustration shows a student struggling with a classroom task.

How the striatum is linked to autism

by  /  9 October 2020

The repetitive behaviors seen in autism may originate in the striatum, a cluster of neurons involved with initiating and executing movements.

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April 2020
White mouse grooming

Gene linked to schizophrenia tied to autism-like behaviors

by  /  23 April 2020

Mice missing DLG2, a protein central to neuronal activity, are anxious, sleep poorly and overgroom themselves.

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February 2020
brain form in the shape of white flowers on black background with the striatum in red

Striatum, the brain’s reward hub, may drive core autism traits

by  /  17 February 2020

Associated primarily with its role in movement, the striatum may also influence the social difficulties of autistic people.

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November 2018
Delicate network of neurons and synapses.

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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September 2018
Photo: Autistic woman Becky Audette lies on a couch under a purple blanket.

Rebooting Becky’s brain

by  /  12 September 2018

An electrical brain implant all but erased the obsessions that had consumed Becky Audette, years after her autism diagnosis. Could similar implants help other people with severe autism?

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August 2018
Two scientists standing in a lab.

Family ties: Sabatini brothers crack codes that may underlie autism

by  /  30 August 2018

David and Bernardo Sabatini, brothers born just a year and a half year apart, invent their way to answering big questions about autism.

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July 2018
a particle of gold and a protective shell nable CRISPR to traverse safely into the brain.

Gene editing via nanoparticles may treat autism syndromes

by  /  5 July 2018

A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.

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January 2018
Protein levels in the brain from birth to about 40 years vary more (blue) or less (red) by brain region but are similar across the lifespan.

Tool tracks brain proteins from infancy to adulthood

by  /  19 January 2018

A new inventory of proteins reveals their levels in seven brain regions from infancy through adulthood.

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