Tag: stem cells

November 2010
News

Video: Why make neurons from children with autism?

by  /  19 November 2010

Ricardo Dolmetsch is making neurons from induced pluripotent stem cells derived from people with Timothy syndrome, a rare single-gene disorder that causes heart arrhythmias and autism. On Wednesday morning at the Society for Neuroscience annual meeting in San Diego, Dolmetsch talked to SFARI about how this approach could help autism research.

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News

Immune protein alters development in young mice

by  /  18 November 2010

Pregnant mice injected with the immune protein interleukin-6 give birth to pups that are less social than normal, an effect that results from the over-activation of two pathways critical in neurodevelopment, researchers reported Tuesday at the Society for Neuroscience annual meeting in San Diego.

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News

Researchers make ‘normal’ neurons in a dish

by  /  16 November 2010

A new model system allows scientists to watch human neurons develop outside of the brain, researchers reported Sunday at the Society for Neuroscience annual meeting in San Diego.

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News

Stem cell assay reveals early development of Rett neurons

by  /  16 November 2010

Researchers have developed the first stem cell system that makes it possible to study the early development of neurons from people with Rett syndrome, a rare disorder on the autism spectrum.

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News

Stem cells reveal neuroligin’s role in development

by  /  15 November 2010

Stem cell studies show that a mutation in the neuroligin-4 gene disrupts the normal development of synapses, the junction between neurons, according to unpublished data shown Sunday at the Society for Neuroscience annual meeting in San Diego.

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October 2010
Opinion

Crossover potential?

by  /  18 October 2010

“I don’t know anything about Williams syndrome”: That isn’t exactly how you’d expect a talk at a meeting on the syndrome to begin, but it happened more than once at a symposium on the disorder last week. Could scientific interchange between Williams syndrome and autism researchers benefit people with either condition?

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September 2010
News

Fragile X protein tied to snags in stem cell development

by  /  13 September 2010

The protein missing in fragile X syndrome is necessary for the proper development of neural stem cells — self-renewing cells that can differentiate into more specialized types, including neurons — according to a paper published in the August issue of Human Molecular Genetics.

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August 2010
News

Fragile X models give clues to stem cell programming

by  /  9 August 2010

Not all stem cells are created equal, a string of new studies suggests: adult cells that are reprogrammed into stem cells carry chemical remnants of the tissue from which they originate, making them distinct from embryonic stem cells. These differences may have important implications for studying fragile X syndrome and other diseases that arise from epigenetic glitches.

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May 2010
News

New technique maps methylated DNA

by  /  14 May 2010

A new technique can simultaneously sequence DNA and pinpoint some of the chemical modifications that turn genes on or off, according to a report published 9 May in Nature Methods. In particular, the technique reveals methyl groups bound to DNA bases.

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June 2009
News

Study links autism to stem cell development

by  /  23 June 2009

The molecular defects that cause some cases of autism may arise during the development of neuronal stem cells, according to a new theory bolstered by several independent animal and human studies.

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