Tag: stem cells

November 2018
View of San Diego in twilight.
News

Takeaways from SfN 2018

by  /  12 November 2018

After the presentation of more than 14,000 abstracts over five days, the Society for Neuroscience annual meeting in San Diego ended last week.

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News

Stem cells could deliver gene therapy for Angelman syndrome

by  /  7 November 2018

Modified stem cells show promise for delivering gene-based therapies to individuals with Angelman syndrome.

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News

‘Mini-brains’ show realistic neuronal firing rhythms

by  /  4 November 2018

Brain organoids made from typical human stem cells begin to show synchronized neuronal firing patterns after growing in a dish for at least four months.

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October 2018
Multimedia / Webinars

Webinar: Patricia Braga discusses stem-cell models of autism

12 December 2018

Register for the next Spectrum webinar, featuring Patricia Braga, who will describe studies of autism involving stem cells.

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Brain cells under magnification glow red, purple and blue.
News

Mini-brains may pin down key genes in large mutations

by  /  22 October 2018

Clusters of brain cells — so-called ‘mini-brains’ grown in the lab — may help researchers understand how large stretches of duplicated or deleted DNA affect the brain.

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Neurons in lab grown brain glow green, red and blue.
News / Toolbox

New techniques extend tool kit for constructing ‘mini-brains’

by  /  5 October 2018

Two new methods for building ‘mini-brains’ may help researchers study how early brain development differs in people with autism.

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June 2018
Week of JuneJun
25th
2018
News / Spotted

Smart genes; Neanderthal mini-brains; diabetes link and more

by  /  29 June 2018

Autism and intelligence share genetic variants, researchers grow Neanderthal mini-brains and see overlap with autism, and maternal diabetes is an autism risk factor.

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May 2018
Blood vessels seen at magnification.
News

Human ‘mini-brains’ make themselves at home in mice

by  /  23 May 2018

Spheres of brain cells derived from people and implanted into mouse brains recruit blood vessels and integrate with mouse neurons.

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February 2018
Week of FebruaryFeb
5th
2018
News / Spotted

Political scientists; folate block; mutational mosaic and more

by  /  9 February 2018

Scientists campaign for elected office in record numbers, folate autoantibodies are common in autism families, and neurons form a genetic mosaic in the brain.

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January 2018
Neurons missing a part of chromosome 16 (left) are larger and have more branches than control neurons (middle); neurons with duplications of the region are small and sport short dendrites (right).
News

Lab-grown neurons showcase effects of autism mutations

by  /  15 January 2018

Neurons derived from people with mutations linked to autism display diverse abnormalities that may help explain the origins of these individuals’ features.

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