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Spectrum: Autism Research News

Tag: spoken version

August 2022
A pregnant woman and a doctor, both masked, have a conversation in an examination room.

U.K. health authority investigates epilepsy drug’s link to autism

by  /  30 August 2022

Prenatal exposure to topiramate increases a child’s autism odds, according to the study that prompted the inquiry, but experts caution that pregnant people with epilepsy have few other options for controlling seizures.

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Illustration of screenlight projecting shadows on the wall of distracted parents: one is on their phone and the other is leaving the room.

Studies investigating link between screen time and autism must improve

by  /  29 August 2022

Showing an association is not enough to determine causation.

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Promising preclinical results prompt Angelman therapy trial

by  /  25 August 2022

Roche’s gene therapy drug Rugonersen boosts expression of the protein missing in the syndrome in mice and monkeys, but whether it works in people remains to be seen.

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Several strands of DNA with different openings at different points to show different functions for the same gene at different points in time

‘Double duty’ autism-linked genes upend conventional characterizations

by  /  23 August 2022

What these genes do and how they affect autism depends on when in development they’re studied, despite what classic ‘gene ontology’ analyses say.

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Illustration of a cassette tape with the tape replaced by a DNA double helix

‘Retro-Cascorder’ tracks gene-expression timing

by  /  19 August 2022

The new tool may help researchers reconstruct the sequence of biological events that underlie development.

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Conceptual illustration of a DNA double helix

Scans of sundry variant types uncover autism-linked genes

by  /  18 August 2022

Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.

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A young boy puts plates on a dining table.

Yen for routine seeds anxiety in autistic children

by  /  16 August 2022

Interventions that moderate a need for ‘sameness’ may prevent anxiety traits.

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Child stands with back to group of large signs offering directions.

Pathological demand avoidance in autism, explained

by  /  11 August 2022

Some clinicians say the term describes a subtype of autism, but others dispute its validity and say it is harmful to the autistic community.

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Mutations disrupting chromatin interactions contribute to autism

by  /  8 August 2022

The mutations occur spontaneously in noncoding stretches of DNA that control gene expression.

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An Ultragenyx employee removes materials from a lab freezer.

Angelman therapy appears safer in restarted trial

by  /  5 August 2022

Interim results from the previously paused trial suggest that doses of the experimental gene therapy drug GTX-102 are well tolerated in children with the autism-linked condition.

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