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Spectrum: Autism Research News

Tag: spoken version

November 2020
Photograph of lab researchers at Ultragenyx

Gene therapy trial for autism-linked condition is put on hold

by  /  5 November 2020

All five participants in a clinical trial of a gene therapy for Angelman syndrome experienced leg weakness, leading sponsors to pause the study.

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Fifteen different drugs commonly prescribed to people with autism created unique behavioral signatures in mice.

‘MoSeq’ identifies drug-specific behaviors in autism mouse model

by  /  2 November 2020

A tool that relies on video cameras and machine learning can identify mice that have mutations in a top autism gene by their behaviors. It also detects how a widely used autism drug affects their movements.

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Group of DNA helixes are seen on black

Analysis combining variants, conditions uncovers hundreds of neurodevelopmental genes

by  /  2 November 2020

The first genetic analysis of multiple types of variants from people with autism or other neurodevelopmental conditions reveals hundreds of genes that may be linked to neurodevelopment.

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October 2020

Integrating molecular data may reveal subgroups of autism

by  /  30 October 2020

An analysis of four molecular datasets shows a distinct signature, including changes in gene expression and chemical DNA modifications, in some autism brains.

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Black mother pushing her child on swing at playground.

First analysis of African autism cohort reveals millions of new variants

by  /  29 October 2020

Genome sequences from a research cohort of autistic African children and their families have revealed more than 4 million novel variants, some of which occur in genes not previously linked to the condition.

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Illustration depicts mother and child facing a field of doors: some are dark and some are light

Low standards corrode quality of popular autism therapy

by  /  28 October 2020

Rapid growth and inadequate standards in the ‘applied behavior analysis’ industry may put vulnerable children in the hands of poorly prepared technicians.

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Illustration shows young woman surrounded by the confusion of puberty and body changes.

Puberty may arrive early for some autistic girls

by  /  27 October 2020

Girls with autism tend to start puberty earlier than their peers do, which may intensify their social difficulties and put them at an increased risk for bullying and mental health conditions such as depression.

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Mature dad and his daughter plays with blocks

Parental age plays small role in large mutations tied to autism

by  /  26 October 2020

Most of the large, spontaneous genetic mutations tied to autism are passed down from fathers. But, unlike with smaller mutations, a parent’s age is unlikely to up the rate at which they occur.

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Adolescent has cheek swabbed

Autism, intellectual disability linked to levels of fragile X protein

by  /  26 October 2020

People with particularly low levels of FMRP, the protein lacking in those with fragile X syndrome, are more likely to also have autism and severe intellectual disability.

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four brain areas marked with flags: Cortex, amygdala, hippocampus, cerebellum

Brain structure changes in autism, explained

by  /  15 October 2020

Autistic people have distinct patterns of brain development, which sometimes result in differences in brain structure. Here’s what we know about those differences.

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