Many people with autism experience a triad of trauma: neglect at home, abuse from trusted adults and bullying at school or work.
The drug popularly known as ecstasy may boost sociability through brain circuits distinct from that underlying its ‘high.’
Neurons in mice that lack an autism gene called CNTNAP2 do not differentiate well between social and nonsocial smells — an issue that seems to stem from haphazard neuronal firing.
Rats missing UBE3A, the gene mutated in people with Angelman syndrome, squeak frequently but tend not to be responsive to the play and squeaks of other rats.
Delivery by cesarean section leads to subtle brain and behavioral alterations in mice, particularly those delivered prematurely.
A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.
A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.
Marmosets exposed to a mock infection in the womb have altered vocal development and diminished social interest; exposed macaques show changes in brain structure and function.