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Tag: social deficits

August 2021
News

Drugs boost serotonin, socialization in multiple autism mouse models

by  /  6 August 2021

The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.

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July 2021
Illustration shows a woman whose mouth is covered by a cloud and whos eyes are covered by a cloud.
News

Double empathy, explained

by  /  22 July 2021

The double empathy theory challenges the idea that social difficulties are specific to autism and suggests that problems arise from a mismatch in perspective between autistic and non-autistic people.

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Illustration shows mouse with colorful wires attached, interacting with another mouse.
Opinion / Viewpoint

How to avoid common pitfalls when parsing circuit control of social behavior

by  /  20 July 2021

When probing the circuits underlying social behavior in animal models of autism, researchers should consider potentially confounding variables, use multiple behavioral assays and report results in a descriptive and unbiased manner.

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Immature inhibitory cells surround mature neuron.
News

Critical time window flagged for autism gene’s influence

by  /  16 July 2021

A transplant of inhibitory neurons during the second week of life prevents social difficulties and a brain signaling imbalance in mice missing a copy of FOXG1.

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Four brown lab mice in a cage, top-down view, with one mouse away from the group.
News

Autism-linked mutation may blur brain’s boundary between self, others

by  /  15 July 2021

A mutation in the autism-linked gene SHANK3 changes how neurons encode information about social agency in mice.

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June 2021
Brain and marijuana leaves
Opinion / Q&A

Q&A with Eric Hollander: Cannabis treatments for autism

by  /  8 June 2021

As cannabis prohibition slowly lifts in the United States, scientists and families in the autism community are increasingly turning to the drug and its constituent compounds to ease autism-related difficulties, including seizures and irritability.

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May 2021
Researcher in red plaid shirt and blue nitrile gloves holds a lab mouse fitted with a fiber optic cannula, a needle-shaped glass piece that goes into the mouse's brain surrounded by a metal sleeve to which researchers attach a fiber optic patch cord.
News

How artificial intelligence is shaking up animal behavior studies in autism

by  /  24 May 2021

Next-generation machine-learning tools are poised to upend how scientists study behavior in animal models of autism — and not everyone is happy about it.

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Humorous photograph shows a young man with plastic sunglasses on that match the patterns around him, surveys a tabletop scene of patterned objects.
Features / Deep Dive

Finding strengths in autism

by  /  12 May 2021

Autism comprises a set of difficulties, but growing evidence suggests that certain abilities also define the condition.

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April 2021
A group of six images of fruit fly brains show networks in green and pink.
News

Poor sleep could be core feature of autism, related conditions

by  /  15 April 2021

Fruit flies with low expression of a gene linked to neurodevelopment have disrupted sleep, poor memory and altered social behavior.

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March 2021
Boy in classroom looks frustrated as other kids interact and move around him.
News

Communication struggles may explain aggression in some autistic boys

by  /  29 March 2021

Poor communication skills predict aggression in autistic boys, according to a new study. In autistic girls, communication and aggression may not be related.

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