Children with autism spend less time in the rapid eye movement stage of sleep than do either controls or those with developmental delays, according to a November report in the Archives of Pediatrics & Adolescent Medicine.
Spectrum: Autism Research News
Two independent groups have created mice that have deletions or duplications in a large section of chromosome 16. Each team has produced an animal with a different set of features, some of which — such as large head size and repetitive behaviors — are reminiscent of people with autism.
The fruit fly is a good model for some of the cognitive defects in fragile X syndrome — but researchers sometimes find themselves having to defend their choice.
A variety of animal models can help researchers better address human-specific questions in neurological disorders such as autism, says Theresa Lee, who has used exotic animal models to study circadian rhythms.
The Simons Simplex Collection (SSC), a database of genetic and clinical information from families that include one child with autism, has gathered data from more than 2,000 different families, researchers report in the October issue of Neuron.
The first genome-wide linkage analysis of more than 1,200 families has identified regions implicated in autism as originating from either the paternal or maternal copies of chromosomes.
Brain imaging reveals distinct signatures in the language circuits of young toddlers with autism while they sleep, according to unpublished data presented yesterday at the IMFAR 2010 meeting in Philadelphia.