Ritalin lowers impulsivity, oppositional behavior and attention deficit in children with autism and has mild side effects, reports a study published 19 June in the Journal of Child and Adolescent Psychiatry.
Spectrum: Autism Research News
RORA, an autism candidate gene, encodes a protein that binds more than 2,500 other genes and alters the expression of some of those genes, according to a study published 22 May in Molecular Autism.
In 2003, John Rubenstein and Michael Merzenich first described the theory, now popular in autism, that the disorder reflects an imbalance between excitation and inhibition in the brain. Takao K. Hensch and Parizad M. Bilimoria review the paper and its impact on the field.
Treating mice that model Rett syndrome with acetyl-L-carnitine delays the onset of symptoms until adulthood, according to a study published 5 December in PLoS One.
Some Chinese individuals with autism have rare mutations that may disrupt the production of melatonin, the hormone that regulates sleep, according to a study published 17 January in PLoS One.
Neurons in mice that model fragile X syndrome show immature, overexcitable firing patterns, particularly during sleep, according to unpublished research presented last week at the Salk Institute, Fondation IPSEN and Nature Symposium on Biological Complexity in La Jolla, California.