This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.
Spectrum: Autism Research News
Tag: simplex families
A massive update to the MSSNG dataset gives qualified researchers ready access to explore autism’s genetic architecture on a cloud-based platform.
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
Common and rare variants in or near autism-associated genes can have opposite effects on cognition.
Spontaneous genetic mutations contribute to autism in 30 to 39 percent of all people with the condition, and 52 to 67 percent of autistic children whose siblings do not also have the condition.
A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.
Genetic sequences from nearly 53,000 people with autism, developmental delay or intellectual disability reveal strong ties to 98 genes.
Brothers and sisters of people with autism are both about two to three times more likely than the general population to have an autistic child themselves.
About 17 percent of children with autism are calmer and more communicative than usual when they have a fever.
Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.