Tag: Simons VIP

April 2019
children playing at a genetic family group meeting
Features / Deep Dive

How families are driving the study of autism genes

by  /  10 April 2019

Parents of children with rare autism-linked mutations are banding together for support and to join forces with scientists, accelerating the pace of research.

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November 2017
Week of NovemberNov
20th
2017
News / Spotted

Relocation repercussions; gene editing first; oxytocin sensor and more

by  /  24 November 2017

The agency that oversees the drug approval process in Europe is moving to Amsterdam, gene editing gets its first human trial, and a tiny sensor detects even a few oxytocin molecules in blood.

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August 2017
Week of AugustAug
7th
2017
News / Spotted

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

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May 2017
News

Chromosome 16 mutations augur distinct developmental paths

by  /  25 May 2017

Children missing a stretch of DNA on chromosome 16 show worsening motor and social skills in the first eight years of life; those with an extra copy of the region do not show this decline.

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August 2016
News

Autism risk region arose during human evolution

by  /  11 August 2016

Humans may be uniquely prone to rearrangements of chromosome 16 that lead to autism, according to preliminary results presented Saturday at the American Society of Human Genetics Annual Meeting in San Diego.

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January 2016
News

DNA from mothers more prone to autism-linked glitches

by  /  18 January 2016

An autism-linked rearrangement on chromosome 16 often occurs on the copy of the chromosome inherited from the mother.

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News

DNA duplication does not dictate intelligence, other traits

by  /  15 January 2016

People with an extra copy of the autism-linked chromosomal region 16p11.2 have a range of characteristics, suggesting that other genetic factors are at play.

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July 2014
Opinion / Q&A

Questions for Nicholas Katsanis: Fishing for autism genes

by  /  1 July 2014

Cell biologist Nicholas Katsanis explains why zebrafish have been key in studying a chromosomal region linked to autism.

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November 2013
News

Close look at autism-linked region reveals complex biology

by  /  27 November 2013

Deletion and duplication of the 16p11.2 chromosomal region have opposite effects on brain size, but produce similar alterations in the brain’s processing of sound. Researchers reported these and other unpublished findings at the 2013 Society for Neuroscience annual meeting in San Diego, painting a complex picture of the region’s role in autism.

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News

Results of 16p11.2 study show promise for autism biomarker

by  /  12 November 2013

The level of activity of a cellular signaling pathway correlates with the degree of social and cognitive impairments in children with an autism-linked genetic abnormality, according to unpublished research presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

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