Researchers have launched an effort to yoke together disparate gene sequencing projects in the U.S., Canada and the U.K., aiming to double the number of known autism-related genes in the next three to four years.
Spectrum: Autism Research News
Tag: Simons Simplex Collection
Analyzing how mutations in people with autism affect gene expression in blood-derived cells could help researchers pinpoint harmful mutations, according to research published 21 July in The American Journal of Human Genetics.
Children with autism carry twice as many new and damaging genetic mutations as typically developing children, according to a new study published in Neuron. The researchers also identified intriguing genetic links between autism and fragile X syndrome.
The largest set of exome sequencing studies of children with autism and their families to date has identified a handful of genes that may increase risk of the disorder, according to research published in Nature.
Researchers have mapped networks of genes expressed at the same time and place in the brain and shown that rare and common autism-linked mutations are likely to function in the same pathways. The results were published 8 March in PLoS Genetics.
Maternal antibodies that attack fetal brain proteins could underlie some cases of autism, says immunologist Betty Diamond.
A consortium of autism researchers, advocates and educators in Rhode Island are aiming to harness the advantages of the state’s small size and tight-knit autism community to build the most comprehensive registry for the disorder yet.
The nation’s largest database of autism research is about to get even bigger, thanks to a partnership between the National Database for Autism Research, a repository of data from 25,000 participants, and the Autism Genetic Research Exchange, a database of 2,500 families.
Individuals who have autism show distinct patterns of gene expression in neurological pathways compared with their unaffected siblings, according to unpublished work presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.