Skip to main content

Spectrum: Autism Research News

Tag: signaling imbalance

January 2014

Genetics: Language gene has limited role in autism

by  /  14 January 2014

Variants in a language gene linked to autism are only modestly associated with the disorder in a large sample, according to a study published 17 October in PLoS One.

Comments
December 2013

Drug fixes cellular defects in autism-related disorder

by  /  2 December 2013

A new stem-cell model of Phelan-McDermid syndrome points to a possible treatment for the rare autism-related disorder, according to a study published in Nature.

Comments
November 2013

Neurons made directly from skin cells model autism mutations

by  /  27 November 2013

Skin cells taken from mice with an autism-linked mutation and transformed directly into neurons have the same properties as neurons from the brains of these mice. The study, published 8 October in Proceedings of the National Academy of Sciences, validates an efficient technique to study disease-linked mutations.

Comments

More or less connected in autism, compared to what?

by  /  19 November 2013

Emerging findings in children with autism are showing both hyperconnectivity and underconnectivity in different regions and circuits throughout the brain.

Comments

New imaging method details brain abnormalities in mice

by  /  14 November 2013

A new imaging technique that can assemble finely detailed pictures of an individual mouse’s brain in less than a day is being used to explore mouse models of autism. Data from the first two models were presented Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.

Comments
Photograph of a tadpole swimming.

First tadpole model of autism surfaces at conference

by  /  11 November 2013

Researchers have recreated one of the most popular rodent models of autism in a decidedly slimier animal: the tadpole. The unpublished study was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.

Comments

Where will the focus on SHANK genes lead?

by  /  11 November 2013

Geneticists react to discoveries and identify next steps for one of autism’s most promising candidate genes.

Comments

SHANK mutations converge at neuronal junctions in autism

by ,  /  5 November 2013

SHANK3, one of the strongest candidate genes for autism, has the potential to be a molecular entry point into understanding the synaptic, developmental and circuit origins of the disorder.
 

Comments
October 2013

Genetics: Autism, epilepsy cases share mutations

by  /  15 October 2013

Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published 12 September in Nature.

Comments
July 2013

Molecular mechanisms: Autism mutation alters brain links

by  /  30 July 2013

Newborn mice with an autism-linked mutation in neuroligin-3, which stabilizes junctions between neurons, have abnormal brain chemistry, according to a study published 4 June in Frontiers in Cellular Neuroscience.

Comments