Genetics: Language gene has limited role in autism
Variants in a language gene linked to autism are only modestly associated with the disorder in a large sample, according to a study published 17 October in PLoS One.
Variants in a language gene linked to autism are only modestly associated with the disorder in a large sample, according to a study published 17 October in PLoS One.
A new stem-cell model of Phelan-McDermid syndrome points to a possible treatment for the rare autism-related disorder, according to a study published in Nature.
Skin cells taken from mice with an autism-linked mutation and transformed directly into neurons have the same properties as neurons from the brains of these mice. The study, published 8 October in Proceedings of the National Academy of Sciences, validates an efficient technique to study disease-linked mutations.
Emerging findings in children with autism are showing both hyperconnectivity and underconnectivity in different regions and circuits throughout the brain.
A new imaging technique that can assemble finely detailed pictures of an individual mouse’s brain in less than a day is being used to explore mouse models of autism. Data from the first two models were presented Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.
Researchers have recreated one of the most popular rodent models of autism in a decidedly slimier animal: the tadpole. The unpublished study was presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
Geneticists react to discoveries and identify next steps for one of autism’s most promising candidate genes.
SHANK3, one of the strongest candidate genes for autism, has the potential to be a molecular entry point into understanding the synaptic, developmental and circuit origins of the disorder.
Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published 12 September in Nature.
Newborn mice with an autism-linked mutation in neuroligin-3, which stabilizes junctions between neurons, have abnormal brain chemistry, according to a study published 4 June in Frontiers in Cellular Neuroscience.