Notable papers in autism research in 2019
This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.
This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.
A shortage of CUL3, a leading autism gene, may impair social behavior in mice by ramping up protein production in neurons.
A mix of two drugs eases hypersensitivity to noise in mice missing an autism gene — offering the promise of a similar treatment for autistic people.
Researchers have analyzed thousands of brain organoids derived from six autistic people, gaining the potential to rapidly screen drugs.
Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?
An experimental drug that muffles the activity of neurons in the skin moderates heightened reactions to touch in six mouse models of autism.
Families of children with mutations in a gene called SYNGAP1 have spurred research into the effects of the mutations on people — and how to treat them.
The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.
An analysis of four mouse models negates certain assumptions underlying the signaling imbalance theory of autism.
A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.