Tag: signaling imbalance

October 2018
News

Study calls into question chemical messenger’s role in autism

by  /  29 October 2018

New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.

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Neurons in lab grown brain glow green, red and blue.
News / Toolbox

New techniques extend tool kit for constructing ‘mini-brains’

by  /  5 October 2018

Two new methods for building ‘mini-brains’ may help researchers study how early brain development differs in people with autism.

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September 2018
Artwork shows a flock of birds flying inside the head of a boy.
Opinion / Viewpoint

How a ‘pacemaker’ for the brain could ease autism traits

by  /  4 September 2018

Looking at the brain as a whole suggests that nudging flawed sets of neurons to collaborate better might alleviate autism traits.

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April 2018
Opinion / Q&A

Autism genes assign starring role to support cells in brain

by  /  24 April 2018

Genes linked to autism are critical to the development of star-shaped brain cells called astrocytes, suggesting a key role for the cells in the condition.

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January 2018
Mice lacking one copy of MEF2C have fewer neurons (red and green, right) in the hippocampus than controls do (left).
News

Modified Alzheimer’s drug may treat some forms of autism

by  /  18 January 2018

A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.

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Neurons missing a part of chromosome 16 (left) are larger and have more branches than control neurons (middle); neurons with duplications of the region are small and sport short dendrites (right).
News

Lab-grown neurons showcase effects of autism mutations

by  /  15 January 2018

Neurons derived from people with mutations linked to autism display diverse abnormalities that may help explain the origins of these individuals’ features.

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black rat and white rat
News

Anxiety drug reverses problems in mice with autism mutation

by  /  4 January 2018

A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.

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August 2017
Week of AugustAug
7th
2017
News / Spotted

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

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News

Flash of light shifts social behavior in autism mice

by  /  2 August 2017

Turning on a set of neurons that dampen brain activity improves social behavior in a mouse model of autism; turning off neurons that excite brain activity does the same thing.

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July 2017
News

Antidepressant eases some autism features in mice

by  /  28 July 2017

A drug that keeps neurons bathed in the chemical messenger serotonin prevents social abnormalities in a mouse model of dup15q syndrome.

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