Tag: SHANK1

July 2011
News

Cognition and behavior: SHANK1 mutant mice keep quiet

by  /  26 July 2011

Mice lacking SHANK1, a member of a family of autism-associated proteins, communicate less with their mothers and potential mates than controls do, according to a study published 9 June in PLoS One.

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March 2011
News / Toolbox

New technique creates map of synapses

by  /  9 March 2011

A new technique can pinpoint the precise location of individual proteins at a synapse — the junction between neurons — at high resolution in brain tissue, according to a study published 9 December in Neuron.

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November 2010
News

Mutant mouse pins PSD-95 in Williams syndrome

by  /  2 November 2010

Mice missing a large protein at the junction between neurons show motor impairments, anxiety and increased social behaviors, according to a study in the American Journal of Psychiatry. The protein, postsynaptic density-95 or PSD-95, is part of a key molecular bridge connecting other proteins linked to autism.

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October 2010
News

Cognition and behavior: SHANK1 mutant mice do not model autism

by  /  25 October 2010

SHANK1 — a member of a family of proteins linked to autism — does not cause autism-like social deficits when mutated in mice, according to a study published online in September in Brain Research.

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February 2010
News / Toolbox

Super-cool synapses

by  /  1 February 2010

A chilling new technique shows the intricate and coordinated activity of previously mysterious pieces of the synapse, the all-important junction between neurons that allows cells to talk to each other.

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