Nothing is known about how the brain changes in aging individuals with autism, according to a review published online 24 August in Gerontology. Nor do researchers know whether the core symptoms of the disorder improve, worsen or remain unchanged with age.
The handful of studies of autism in Africa suggest that only the most severely affected children are seen in clinics.
A compound that shows promise as a treatment for fragile X syndrome alleviates repetitive behaviors in mice, but unexpectedly makes them less social.
By comparing the DNA of thousands of children who have developmental disabilities to that of controls, researchers have identified numerous mutations likely to contribute to disease.
Marriages between first cousins are frowned upon in the U.S. and western Europe, but they are common throughout much of the world. A new study shows that these consanguineous unions can help researchers uncover genetic risk factors for neurodevelopmental diseases.
An ingenious new technique may allow small brain implants to release chemicals when and where they are needed, according to a study published 2 June in the Journal of Neural Engineering.
Blocking a chemical messenger — a much-touted approach to treating fragile X syndrome — is unlikely to completely reverse symptoms of the disorder, according to a provocative new study. The results, published in May in Behavioural Brain Research, show only modest behavioral improvements with the approach.
A plan by an American Psychiatric Association revision committee to remove Rett syndrome from the Diagnostic and Statistical Manual of Mental Disorders (DSM) has sparked concern among some parents and researchers. But proponents of the change say the plan has been widely misunderstood, and their goal is better treatment for people with the neurodevelopmental disorder.
A new mouse model of 15q duplication syndrome, a genetic disorder associated with autism, falls short of recapitulating the symptoms of the syndrome. But it nonetheless points to a cluster of well-known risk genes as the most likely culprits.
Roughly one-quarter of individuals with Dravet syndrome, a syndromic form of epilepsy that starts in infancy, also have autism, according to a study published 25 May in Epilepsy and Behavior.