Individuals who carry a large and rare deletion on chromosome 16 that is associated with autism are likely to have developmental delays, be obese or both, according to two studies published last week in Nature.

Autism may be the result of faulty wiring that occurs during early brain development, according to two independent studies that looked at the origins of circuit disruption.

Deletions or duplications of chromosomal segment 16p11.2 — previously reported as a key autism region — are seen in people with developmental delays and speech and behavioral problems, but not necessarily autism. That’s the finding from two large studies published last week of people carrying these rare genetic variations.

Genetic analysis of one Belgian family with a history of autism has pinpointed a piece of DNA on chromosome 16, within a segment thought to be missing in about one percent of all cases of autism. The unpublished data was presented on Saturday at the World Congress of Psychiatric Genetics in San Diego.

The Psychiatric GWAS Consortium has released its first batch of analyses, identifying several significant common variations associated with schizophrenia. The results were presented Sunday at the World Congress of Psychiatric Genetics in San Diego.

Scientists have identified several autism-specific variants in a gene that lies within a chromosomal region linked to the disorder, according to a poster presented at the World Congress of Psychiatric Genetics in San Diego.

Variations linked to autism and schizophrenia crop up in people with a large variety of conditions, including bipolar disorder, seizures and obsessive-compulsive disorder, as well as in healthy people. This notion gained new support from unpublished data presented at the World Congress for Psychiatric Genetics in San Diego.

Mice carrying an autism-associated mutation show impaired social interactions and dramatic changes in brain size when their immune systems are activated, according to research presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.

Computer software that maps the three dimensions of the brain has found that people with schizophrenia have deep grooves and small volumes in brain areas associated with planning and executive control.

Tracy Bale, associate professor of neuroscience at the University of Pennsylvania, talks about what she calls her “big soapbox issue”: the fallacious idea of a true animal model for a human psychiatric disease — and the pitfalls of over-interpreting rodent behavior.